Accelerated Molecular Dynamics and Protein Conformational Change: A Theoretical and Practical Guide Using a Membrane Embedded Model Neurotransmitter Transporter

. Author manuscript; available in PMC: 2016 Jan 1.

Published in final edited form as: Methods Mol Biol. 2015;1215:253–287. doi: 10.1007/978-1-4939-1465-4_12

Fig. 2. Graphical representation of a hypothetical potential energy function and different bias potentials plotted at various α values and at a relatively low threshold boost energy, E.