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. 2015 May 13;101(16):1302–1308. doi: 10.1136/heartjnl-2015-307438

Table 2.

HR (95% CI) for atrial fibrillation according to indexed left atrial (LA) size, mitral Doppler groups and mitral Doppler flow

All Model 1 Model 2 Model 3 Model 4 Model 5
Indexed LA size
 1 (<2.2) 1 (Ref.) 1 (Ref.) 1 (Ref.) 1 (Ref.) 1 (Ref.)
 2 (2.2–2.79) 1.4 (1.1 to 1.7) 1.6 (1.2 to 2.0) 1.6 (1.3 to 2.0) 1.6 (1.2 to 2.0) 1.4 (1.1 to 1.8)
 3 (≥2.8) 3.1 (2.1 to 4.4) 4.2 (2.7 to 6.5) 4.2 (2.7 to 6.5) 4.1 (2.6 to 6.4) 4.0 (2.5 to 6.4)
(p for trend <0.0001) (p for trend <0.0001) (p for trend <0.0001) (p for trend <0.0001) (p for trend <0.0001)
Mitral Doppler groups
 Group I 1 (Ref.) 1 (Ref.) 1 (Ref.) 1 (Ref.)
 Group II 1.6 (1.0 to 2.7) 1.8 (1.1 to 3.0) 1.5 (0.9 to 2.6) 1.6 (0.9 to 2.9)
 Group III 1.1 (0.9 to 1.4) 1.1 (0.9 to 1.4) 1.2 (0.9 to 1.6) 1.1 (0.9 to 1.5)
 Group IV 1.7 (1.0 to 3.0) 1.5 (0.8 to 3.1) 1.5 (0.7 to 2.9) 1.2 (0.5 to 3.0)
(p Value for trend 0.103) (p Value for trend 0.141) (p Value for trend 0.051) (p Value for trend 0.240)
Abnormal mitral Doppler flow 1.2 (1.0 to 1.5) 1.2 (1.0 to 1.5) 1.3 (1.0 to 1.6) 1.2 (0.9 to 1.5)
(Group II–IV) (p Value 0.081) (p Value 0.086) (p Value 0.034) (p Value 0.159)

The Tromsø Study, 1994–2010.

Model 1: adjusted for age and sex.

Model 2: as Model 1+height, body mass index, hypertension, diabetes, palpitation.

Model 3: as Model 2+abnormal mitral Doppler flow (only in indexed LA size), LA size (only in mitral Doppler groups and flow).

Model 4: as Model 2+mitral Doppler groups (only in indexed LA size) or LA size (only in mitral Doppler groups and flow).

Model 5: as Model 2, participants with coronary heart disease, valvular heart disease, heart failure or hypertrophy at baseline excluded.

Mitral Doppler groups: Group I E/A ratio 0.75–1.5 and E-wave deceleration time (EDT >140 ms; group II E/A ratio >1.5 and EDT >140 ms; group III E/A ratio <0.75 and any EDT; group IV E/A ratio >0.75 and EDT <140 ms.

Ref; reference.