Table 1.
The basic characteristics of the included studies addressing rs11196218.
| First author | Publication year | Region | Source of controls | Sample sizes | Cases | Controls | HWE | Comparability | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Case | Control | G | A | G | A | ||||||
| Ng | 2007 | Hong Kong | Community-based and hospital staff | 433 | 419 | 676 | 190 | 599 | 239 | Yes | Age*, sex*, BMI** |
| Zhang | 2008 | Hunan | Hospital-based | 536 | 475 | 716 | 272 | 623 | 221 | Yes | Age*, sex**, BMI* |
| Luo | 2009 | Beijing | Hospital-based | 500 | 500 | 684 | 252 | 696 | 240 | No | Age**, sex**, BMI** |
| Ma | 2010 | Shanghai | Hospital-based | 259 | 200 | 309 | 209 | 240 | 168 | Yes | Age**, sex*, BMI** |
| Lin | 2010 | Chengdu | Hospital-based | 1529 | 1439 | 2171 | 887 | 2015 | 863 | Yes | Age**, sex*, BMI** |
| Wen | 2010 | Shanghai | N/D | 1165 | 1136 | 1699 | 629 | 1677 | 595 | No | Age*, sex*, BMI* |
| Zhu | 2011 | Anhui | Hospital-based | 300 | 300 | 156 | 444 | 122 | 478 | Yes | Age*, sex*, BMI* |
| Zheng | 2012 | Chongqing | Hospital-based | 227 | 152 | 340 | 114 | 218 | 86 | Yes | Age*, sex**, BMI** |
| Qiao | 2012 | Harbin | Hospital-based | 700 | 560 | 1025 | 367 | 819 | 295 | Yes | Age*, sex*, BMI* |
| Zhai | 2014 | Henan | Community-based and Hospital-based | 1842 | 7777 | 2639 | 967 | 111287 | 4041 | Yes | Age**, sex**, BMI** |
Abbreviations: HWE, Hardy-Weinberg equilibrium; Yes, the genotype distribution conformed to HWE in the control group; No, the genotype distribution not conform to HWE in the control group;
Hospital-based: subjects who were enrolled from health checks conducted at the hospital; community-based and hospital staff: subjects who were enrolled from the community and hospital staff; N/D: no description; *: p>0.05; **: p<0.05.