Figure 3. Time courses from selected regions of interest (ROIs) for Drawing vs. Scribbling (A) and Drawing and Scribbling vs. Baseline (B).

For demonstrative purposes, we also present the time-course of all experimental conditions in different ROIs using the peak voxel in the smoothed volume of each ROI. (A) Several ROIs in the occipital cortex show robust and selective activation for drawing objects with a typical hemodynamic response. Each ROI (corresponding to the green scale clusters shown in Figure 2) can be identified by its header. A similar pattern was also found in clusters within the parietal cortex. Robust activation for drawing was also found in prefrontal cortex, but in these areas there was also relatively robust activation for imagery and naming/verbal memory (in spite of the fact that these conditions were ignored in the contrast used to select the ROIs in this test). (B) ROIs of peak activation for clusters significantly activated by drawing and scribbling versus baseline (similar to those shown in Figure 2 in red to yellow color scale). The time courses are depicted by the following color index: tactile objects (red), mental imagery (brown), drawing (blue), scribbling (cyan), motor control (orange) and naming/verbal memory (green).