Table 1.
TA Muscle In Vivo Functional Capacity Twelve Weeks Postinjury
| Uninjured | TEMR | |||||
|---|---|---|---|---|---|---|
| Unoperated | Sham/Ablation | No repair | BAM | Negative | Positive | |
| Sample size (n) | 8 | 6 | 4 | 7 | 7 | 6 |
| Body Wt. (g) | 243±7 | 252±13 | 254±18 | 241±9 | 259±7 | 243±7 |
| TA muscle wet Wt. (mg) | 423±16a | 446±36a | 342±28b | 386±14a,b | 356±6b | 390±14a,b |
| Peak tetanic isometric torque | ||||||
| Nmm/kg body wt | 107.9±4.0a | 87.5±8.9b | 60.9±2.1c | 67.9±2.9c | 56.1±3.4c | 77.1±1.7b |
| % Deficit | 19* | 30† | 22† | 36† | 12† | |
| Nmm/g TA wet wt. | 49.9±1.9a,# | 49.4±3.8a | 45.3±2.3a,b | 41.7±2.2b | 40.7±2.3b | 48.2±1.0a |
Values are mean±SEM. Values denoted with the same letter are not significantly different (p>0.05), while values without a like letter denotation are significantly different (p<0.05).
Deficit calculated from unoperated. †Deficit calculated from sham/ablation. #Unoperated values were normalized to the wet weight of all anterior crural muscles.
BAM, bladder acellular matrix; TA, tibialis anterior; TEMR, tissue engineered muscle repair.