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Gingival oral squamous cell carcinoma; cat, case No. 7. (a) PTHrP-positive reaction. Moderate PTHrP staining was detected in the cytoplasm (white arrow) and nuclei (black arrows) of OSCC cells. Fibrous stroma (desmoplasia) indicated by white asterisk. (b) PTHrP-negative control. Preincubation of the PTHrP primary antibody with PTHrP blocking peptide eliminated staining (white arrow = OSCC cell, black arrows = nuclei, white asterisk = desmoplasia). Diaminobenzidine, no counterstain.
