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. Author manuscript; available in PMC: 2015 Jul 29.
Published in final edited form as: Vet Pathol. 2010 Oct 12;48(1):302–312. doi: 10.1177/0300985810384414

Figure 20.

Figure 20

Parathyroid hormone-related protein–positive (PTHrP-positive) oral squamous cell carcinoma (OSCC) cells and PTHrP-positive nuclei are more frequent in biopsies with evidence of osteolysis. Each bar represents 100% of biopsies in each group (with and without evidence of osteolysis). Each bar is subdivided to demonstrate the proportion of biopsies with 0 to 24%, 25 to 49%, 50 to 74%, and 75 to 100% PTHrP-positive cells or PTHrP-positive nuclei, as indicated. PTHrP-positive tumor cells were more common in biopsies with osteolysis, compared to OSCC without osteolysis (*P = .001). PTHrP-positive tumor nuclei were more common in biopsies with osteolysis, compared to OSCC without osteolysis (*P < .0001).