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. 2015 Jul 29;11(7):e1005401. doi: 10.1371/journal.pgen.1005401

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© 2015 Hamazaki et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 1 — (A) Genotype frequencies of embryos produced from Adrm1 ^+/- (Rpn13 ^+/-) mouse intercrosses. Numbers in parenthesis indicate resorbed fetuses or dead newborns. E: Embryonic day, P: Postnatal day. (B) Gross appearance of control and Rpn13KO littermates shortly after birth. (C) Skeletal analysis of E18.5 littermates by Alzarin red (bone) and Alcian blue (cartilage) staining. (D) Immunohistochemical analysis of sagittally sectioned E18.5 littermates by Rpn13 antibody. (E) Survival curves of newborn mice. Control and Rpn13KO mice were delivered by cesarean section.