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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Adv Drug Deliv Rev. 2014 Nov 21;84:222–239. doi: 10.1016/j.addr.2014.11.015

Table 5.

Use of gene transfer to address additional aspects of tendinopathy.

Gene Vector Delivery mode Species, indication Reference
Sox-9 Adenovirus In vivo Rabbit, bone–tendon junction [222]
IGF-1 Adenovirus Ex vivo/MSC Horse, tendinitis [217]
BMP-4 Lentivirus In vivo Rat, tendon insertion site [218]
BMP-2 Adenovirus In vivo Rabbit, tendon insertion site [219]
MT1-MMP Adenovirus Ex vivo/MSC Rat, tendon insertion site [221]
siRNA-Runx2 Adenovirus In vivo Mouse, heterotopic ossification [223]
siRNA-Runx2, SMAD4 Adenovirus In vivo Rat, hetertopic ossification [224]
shRNA-Decorin Lentivirus Ex vivo/tendon cells Rat, patellar tendon [225]