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. 2015 Jul 29;10(7):e0133873. doi: 10.1371/journal.pone.0133873

Fig 4. TI in the presence of RNAP pause sites.

Fig 4

(A) Mechanistic representation of RNAP collision in presence of two pause sites in the sense strand at positions 160 bp (xk/L = 0.4) and 320 bp (xk/L = 0.8). Pause times are 2 s. Increased production of truncated RNA at the pause sites due to enhanced probability of collision is indicated by arrows. (B) Switch response in x levels maintains sharpness as pause time increases but the dynamic range of x is widened more than one order of magnitude. H denotes the value of Hill coefficient (see Methods). (C) Expression maps for truncated and full-length RNA from pX at different pause times. Truncated RNA production increases as pause time increases. (D) Expression maps for truncated and full-length RNA from pY at different pause times.