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. 2015 Jul 29;10(7):e0134349. doi: 10.1371/journal.pone.0134349

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© 2015 Lacy et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 4 — Intent-to-treat Population; % improvement in abdominal bloating at week 12 (end of the treatment period). Note: The distribution of % improvement in abdominal bloating at week 12 was a secondary endpoint for both linaclotide dose groups. (P < 0.01 for both linaclotide groups vs. placebo; P values were obtained from a Kolmogorov-Smirnov test for equality of distribution.)