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. 2015 Jul 29;10(7):e0134080. doi: 10.1371/journal.pone.0134080

Table 1. Reduction in viral load of infected duck embryonic fibroblast (DEF) cells following treatment with Ribavirin.

PaBV-4 positive cell foci Area of infected cells (%)
Virus (ffu) Ribavirin (μg/mL) Median (25th– 75th percentile) Median (25th– 75th percentile)
64 0 36 35–37 47.7 47.2–48.2
0.25 40 33–46 49.5 46.7–52.3
2.5 73 72–73 30.6 29.0–32.2
25.0 1 0.5–1.5 0.4 0.4–0.5
7 0 50 48–51 9.1 8.5–9.8
0.25 73 72–73 12.5 12.0–13.0
2.5 19 18–20 4.3 4.1–4.5
25.0 2 2–2 0.5 0.4–0.5
1 0 7 6–7 1.6 1.5–1.6
0.25 7 6–9 1.3 1.0–1.6
2.5 4 3–4 0.9 0.9–0.9
25.0 1 0–1 0.6 0.6–0.6
No virus (negative control) 0 0 0 0.2 0.2–0.3
0.25 1 0.5–1.5 0.2 0.2–0.2
2.5 0 0 0.4 0.4–0.4
25.0 1 0.5–1.5 0.7 0.6–0.8

Cells infected with 0.05 and 0.005 ffu had PaBV-4 positive cell foci and percent area of infected cells similar to No virus (negative control).