Skip to main content
. 2015 Jul 29;11(7):e1005065. doi: 10.1371/journal.ppat.1005065

Fig 3. IL-27 signaling is required to prevent liver immunopathology during infection with T. congolense.

Fig 3

(A) Macroscopic examination of liver on day 10 after infection with T. congolense revealed the presence of extensive pale geographic areas in IL-27R-/- (WSX-1-/-), but not wild-type mice (n = 4). (B) Hematoxylin and eosin staining showing loss of hepatocyte cellular architecture in the liver of IL-27R-/-, but not wild-type mice (n = 4) on day 10 after infection with T. congolense (original magnification ×40). (C) Serum ALT activities were assessed in IL-27R-/- and wild-type mice (n = 4) on day 7 and 10 after infection with T. congolense. Data are presented as the mean ± SEM. The results presented are representative of 2 separate experiments.