Table 4. The first ten high scoring ligands for human-mouse OR pair 2.
The human-mouse OR pair 2 has the maximum sequence identity of 84%. The highest scoring ligand is Helional for the two ORs, while there are only 4 common ligands out of the ten high scoring ligands (shown in bold font). The ligands that are dissimilar are from different clusters in ligand clustering analysis (Column 3 and 6).
| Odorant | Gscore kcal/mol (Human OR GI: 289547623 (1A1) | Ligand Cluster Number | Odorant | Gscore kcal/mol (Mouse OR GI: 18480066 (MOR125-1) | Ligand Cluster Number |
|---|---|---|---|---|---|
| Helional | -8.51 | 15 | Helional | -10.96 | 15 |
| Ethyl-vanillin | -7.32 | 8 | Androstadienone | -9.50 | 23 |
| Hedione | -7.30 | 33_4 | Androstenone | -8.36 | 23 |
| Cumarin | -7.22 | 9 | Nonanoic acid | -7.71 | 33_2 |
| Methyl salicylate | -7.17 | 14 | Indole | -7.56 | 12 |
| Piperonyl acetone | -7.13 | 18 | Methyl salicylate | -7.56 | 14 |
| Thymol | -7.09 | 17 | Piperonyl acetone | -7.35 | 18 |
| Vanillin | -7.08 | 8 | Butyric acid | -7.23 | 31 |
| Menthol | -7.08 | 21 | Lyral | -7.21 | 27 |
| Androstadienone | -7.04 | 23 | Octanoic acid | -7.18 | 33_2 |