Table 7. Average difference in binding energies (kcal/mol) of odorants to 10 human-mouse OR pairs.

The average binding energies of 125 odorants to each of the ORs were calculated and the difference in the average energy between each human-mouse OR pair has been reported. The OR pair 2 (with the highest sequence identity of 84%) has the minimum difference in binding energy.

OR pair	Average difference in binding energies to odorants(kcal/mol)	% Identity between the OR pairs
OR pair 1	0.59	49
OR pair 2	0.01	84
OR pair 3	0.08	54
OR pair 4	1.97	76
OR pair 5	0.45	72
OR pair 6	1.74	43
OR pair 7	0.32	63
OR pair 8	1.17	61
OR pair 9	0.03	81
OR pair 10	0.65	76