Table 10. Average gscore (kcal/mol) for interactions between aldehydes in the odorant dataset to the 10 human-mouse OR pairs.

The average binding energy of each of the aldehyde to the 20 ORs was calculated. Helional is known to be the most potent aldehyde as compared to aldehydes with 5–10 carbon atoms.

Odorant (aldehyde)	Average gscore (kcal/mol) of binding to 10 human-mouse OR pairs
Helional	-5.66
Butanal	-2.36
Pentanal	-2.21
Hexanal	-2.17
Heptanal	-2.35
Octanal	-2.75
Nonanal	-3.09
Decanal	-2.49