TABLE 1.
Amyloid and TTR deposition in human young normal, aged normal and OA cartilage.
| Group | Age | Sex | OA grade | Congo red | TTR |
|---|---|---|---|---|---|
| Young Normal | 16 | M | 1 | − | − |
| 22 | F | 1 | − | − | |
| 23 | F | 1 | − | − | |
| 24 | M | 1 | − | − | |
| 24 | M | 1 | − | + | |
| 29 | M | 1 | − | − | |
| 33 | M | 1 | − | − | |
| 36 | M | 1 | − | − | |
| 36 | F | 1 | − | − | |
| 40 | M | 1 | − | − | |
| 41 | M | 1 | − | − | |
| 48 | F | 1 | − | − | |
| Aged Normal | 68 | F | 1 | − | + |
| 70 | M | 2 | − | + | |
| 70 | F | 1 | − | − | |
| 74 | M | 1 | − | + | |
| 74 | F | 2 | + | + | |
| 75 | F | 1 | + | − | |
| 76 | M | 1 | + | + | |
| 76 | F | 1 | − | + | |
| 77 | M | 1 | + | + | |
| 78 | F | 2 | + | + | |
| 79 | F | 1 | + | + | |
| 94 | F | 1 | + | + | |
| Osteoarthritis | 49 | F | 3 | + | + |
| 59 | F | 4 | + | + | |
| 62 | F | 3 | + | + | |
| 64 | M | 3 | + | + | |
| 77 | F | 3 | + | + | |
| 80 | M | 3 | + | + | |
| 82 | M | 4 | + | + | |
| 84 | M | 3 | + | + | |
| 84 | F | 4 | + | + | |
| 88 | F | 3 | + | + | |
| 89 | F | 4 | + | + | |
| 90 | F | 4 | + | + | |
Cartilage sections from 12 young normal, 12 aged normal, and 12 OA donors were stained with Congo red and antibodies to human TTR.
The presence of staining is marked as (+).