Table 4.

Variations in Pain Levels (mean worst pain score) Among Tested SNPs of the COX-1, and COX-2 Genes

SNPs	Genotype	Number of subjects	Genotypes Frequencies	Mean (SE) Worst Pain	ANOVA R2	P-value	Gene
rs2206593	A/G	6	0.118	3.7 (0.8)	0.099	0.025*	COX-2
	G/G	45	0.882	1.6 (0.3)
rs2383515	G/G	29	0.569	2.3 (0.4)	0.056	0.094	COX-2
	G/T	22	0.431	1.3 (0.4)
rs5275	C/C	7	0.200	1.3 (0.7)	0.12	0.12	COX-2
	C/T	15	0.429	1.5 (0.5)
	T/T	13	0.371	2.8 (0.5)
rs5277	C/C	1	0.020	2.0 (2.1)	0.010	0.77	COX-2
	C/G	12	0.235	1.5 (0.6)
	G/G	38	0.745	2.0 (0.3)
rs1236913	C/C	47	0.922	1.7(0.3)	0.069	0.062	COX-1
	C/T	4	0.078	3.8(1.0)
rs3842803	C/T	2	0.039	0.0(1.5)	0.033	0.20	COX-1
	T/T	49	0.961	2.0(0.3)
rs10306202	A/A	1	0.020	0.0(2.1)	0.034	0.43	COX-1
	A/G	11	0.216	2.5(0.6)
	G/G	39	0.765	1.8(0.3)
rs5789	A/C	1	0.020	0.0(2.0)	0.016	0.37	COX-1
	C/C	50	0.980	1.9(0.3)
rs10306114	A/A	44	0.863	2.0(0.3)	0.032	0.46	COX-1
	A/G	5	0.098	1.2(0.9)
	G/G	2	0.039	0.5(1.5)
rs1213266	A/A	1	0.020	0.0(2.1)	0.017	0.67	COX-1
	A/G	10	0.196	1.9(0.7)
	G/G	40	0.784	1.9(0.3)
rs3842788	A/A	1	0.020	0.0(2.1)	0.017	0.67	COX-1
	A/G	10	0.196	1.9(0.7)
	G/G	40	0.784	1.9(0.3)