Table 1.
Group | Baseline CBF |
Ischemia CBF |
Reperfusion CBF |
Excluded (n) |
Mortality (n) |
---|---|---|---|---|---|
Every Other Day Veh | 100 | 11.9±4.46 | 62.2±25.32 | 0 | 6 |
Every Other Day RPC | 100 | 10.0±4.09 | 75.4±56.28 | 4 | 2 |
Every Day Veh | 100 | 11.9±4.89 | 72.2±23.93 | 3 | 2 |
Every Day RPC | 100 | 9.7±3.89 | 59.4±36.87 | 2 | 2 |
Intermittent Veh | 100 | 11.3±3.17 | 67.4±28.34 | 2 | 6 |
Intermittent RPC | 100 | 11.5±3.76 | 68.5±28.14 | 4 | 4 |
Single Veh | 100 | 11.61±3.36 | 65.43±17.33 | 1 | 0 |
Single RPC | 100 | 11.35±5.32 | 71.24±22.27 | 0 | 1 |
Total | 16 | 23 |
Laser-Doppler flowmetry was used to measure CBF for inclusion/exclusion. Measurements are taken 1) baseline prior to occlusion, 2) ischemia immediately after occlusion is initiated and 3) reperfusion immediately after occlusion is removed. Values are represented as % of baseline±SD.
Mice were excluded the study if they did not reach ≤80% drop in blood flow from baseline.
Mortality figures illustrate mice who died <24 hours following MCAo.