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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Am J Obstet Gynecol. 2015 Mar 25;213(2):204.e1–204.e6. doi: 10.1016/j.ajog.2015.03.045

Table 2. The Association of Reproductive Hormones with Innate Antiviral Activity.

Group Number HSV-1 Suppression vs. Control (%) HSV-2 Suppression vs. Control (%) HIV-1 Suppression vs. Control (%) Ratio of CVL Protein Content (Premenopausal: Postmenopausal)
Postmenopausal 29 23.22 ± 15.46 36.56 ± 29.36 10.96 ± 29.41* 1
Days 1-14 26 31.20 ± 15.91 40.23 ± 31.50 39.29 ± 40.57 2.2
Days 15-28 27 30.21 ± 29.38 39.26 ± 36.85 26.49 ± 38.45 2.6
OCP 27 28.09 ± 21.18 52.86 ± 24.42 35.77 ± 31.72 2.7
DMPA 28 31.95 ± 22.03 38.25 ± 41.61 32.95 ± 35.00 1.8
LNG-IUD 28 25.09 ± 26.34 48.18 ± 30.55 37.88 ± 37.22 3.1
P-Value** 0.63 0.38 0.04*** <0.001
*

One postmenopausal result outlier excluded.

**

P-value from one way analysis of variance

***

HIV-1 suppression was lower among postmenopausal women compared to reproductive-aged women (11% vs. 34%, respectively; P=0.002)