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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Mol Neurobiol. 2015 Jan 29;53(2):1329–1342. doi: 10.1007/s12035-015-9094-5

Figure 7. σ-1R is critical for cocaine-induced GFAP expression.

Figure 7

Pretreatment of A172 with the σ-1R antagonist BD1047 inhibited cocaine-mediated induction of Egr-1 expression (a) and GFAP expression (b). σ-1R siRNA but not non-specific siRNA inhibited cocaine-mediated induction of Egr-1 (c) and GFAP (d) expression. All the data are presented as mean±SEM of four individual experiments. *p<0.05, **p<0.01 vs control group; #p<0.05, ##p<0.01 vs cocaine-treated group.