Table 4.
Genotype frequencies of APE1 gene polymorphism in breast cancer cases ER.
| Genotype | Cases | Controls | OR | 95% CI | χ 2 | p value |
|---|---|---|---|---|---|---|
| rs1130409 | ER +ve | |||||
| Asp/Asp | 7 (0.127) | 27 (0.27) | Ref | |||
| Asp/Glu | 23 (0.418) | 46 (0.46) | 1.929 | 0.731–5.089 | 1.79 | 0.18065 |
| Glu/Glu | 25 (0.454) | 27 (0.27) | 3.571 | 1.322–9.645 | 6.65 | 0.00992 |
| Asp/Glu + Glu/Glu | 48 (0.872) | 73 (0.73) | 2.536 | 1.023–6.286 | 4.22 | 0.03992 |
| Asp | 37 (0.336) | 100 (0.5) | Ref | |||
| Glu | 73 (0.663) | 100 (0.5) | 1.973 | 1.217–3.198 | 7.71 | 0.00551 |
| rs1130409 | ER −ve | |||||
| Asp/Asp | 5 (0.111) | 27 (0.27) | Ref | |||
| Asp/Glu | 22 (0.488) | 46 (0.46) | 2.583 | 0.876–7.613 | 3.09 | 0.07881 |
| Glu/Glu | 18 (0.4) | 27 (0.27) | 3.600 | 1.168–11.09 | 5.30 | 0.02127 |
| Asp/Glu + Glu/Glu | 40 (0.888) | 73 (0.73) | 2.959 | 1.057–8.281 | 4.56 | 0.03281 |
| Asp | 32 (0.355) | 100 (0.5) | Ref | |||
| Glu | 58 (0.644) | 100 (0.5) | 1.812 | 1.085–3.027 | 5.22 | 0.02230 |