Table 2.
CINV per chemotherapy and phase
| CINV | Overall | Carboplatin | CRC (oxa/iri) |
|---|---|---|---|
| Total period | n = 231 | n = 99 | n = 110 |
| Vomiting | 48 (20.8) | 22 (22.2) | 19 (17.3) |
| Nausea | 97 (42.0) | 47 (47.5) | 41 (37.3) |
| Significant nausea | 55 (23.8) | 25 (25.3) | 25 (22.7) |
| No CINV | 128 (55.4) | 51 (52.5) | 66 (60.0) |
| CINV | 103 (44.6) | 48 (48.5) | 44 (40.0) |
| Acute Phase | n = 180 | n = 81 | n = 83 |
| Vomiting | 17 (9.2) | 11 (13.6) | 3 (3.6) |
| Nausea | 42 (23.3) | 21 (25.9) | 18 (21.7) |
| Significant nausea | 17 (9.4) | 7 (8.6) | 9 (10.8) |
| No CINV | 137 (76.1) | 59 (72.8) | 65 (78.3) |
| CINV | 43 (23.9) | 22 (27.2) | 18 (21.7) |
| Delayed phase | n = 231 | n = 99 | n = 110 |
| Vomiting | 38 (16.5) | 15 (15.2) | 17 (15.5) |
| Nausea | 89 (38.5) | 44 (44.4) | 38 (34.5) |
| Significant nausea | 50 (21.6) | 22 (22.2) | 23 (20.9) |
| No CINV | 136 (58.9) | 54 (54.5) | 69 (62.7) |
| CINV | 95 (41.1) | 45 (45.5) | 41 (37.3) |
Nausea: VAS > 5 mm; significant nausea: 25 mm < VAS < 100 mm; acute phase: first 24 h after MEC treatment; delayed phase: after first 24 h after MEC treatment
CINV chemotherapy-induced nausea and vomiting