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Average core body temperature plotted hourly for the first 4 h of the 20 h recording period for mice trained with signaled, escapable shock (SES, A) or signaled, inescapable shock (SIS, B) training. Average temperature is shown for baseline (Base), handling control (HC), and for ICV microinjections of saline (SAL), corticotropin releasing factor (CRF), and astressin (AST) prior to SES (n = 9) or SIS (n = 9). Comparisons to Base: *p < 0.05. Values are means ± SEM.
