Table 2.
Total sleep, NREM and wake parameters for the 8 h light period and 12 h dark period during baseline (Base), handling control (HC), and for days on which the mice received ICV injections of saline (Sal), corticotropin releasing factor (CRF) or astressin (AST) prior to training with signaled, escapable shock (SES) or signaled, inescapable shock (SIS).
| Base | HC | Sal | CRF | AST | ||
|---|---|---|---|---|---|---|
| LIGHT PERIOD | ||||||
| Total sleep | SES | 211.4±19.7 | 269.3±21.0 | 231.5±19.2 | 182.8±14.2#∧ | 239.7±24.1 |
| SIS | 250.8±20.6 | 259.9±16.6 | 254.3±10.9 | 241.1±7.6#∧ | 270±16.9 | |
| NREM total | SES | 198±18.0 | 253.8±19.7 | 218.2±18.7 | 177.1±13.1# | 224.6±20.8 |
| SIS | 234.4±19.3 | 243.7±15.0 | 245.2±10.0 | 234.9±7.5# | 258.3±16.3 | |
| NREM episodes | SES | 116.9±16.3 | 1.22±11.9 | 159.4±14.8* | 133.6±18.4* | 140.6±11.2 |
| SIS | 150.9±13.8 | 143.6±10.8 | 192.9±13.4 | 198.7±13.0 | 168.7±12.8 | |
| NREM duration | SES | 1.70±0.18 | 1.86±0.22 | 1.26±0.15# | 1.44±0.24# | 1.56±0.22 |
| SIS | 1.49±0.19 | 1.53±0.16 | 1.10±0.06# | 1.12±0.10# | 1.36±0.12 | |
| Active wake | SES | 132.8±20.0 | 96.3±17.0 | 111.6±18.9 | 134.7±21.2 | 130.5±22.0 |
| SIS | 89.1±11.7 | 99.9±11.7 | 85.8±11.2 | 91.2±6.5 | 89.9±14.1 | |
| Quiet wake | SES | 135.8±9.7#∧ | 114.5±9.5 | 136.9±12.8#∧ | 162.6±13.2#∧ | 109.7±7.1 |
| SIS | 140.1±14.6#∧ | 120.3±8.3 | 139.9±4.7#∧ | 147.7±6.4#∧ | 120.1±7.9 | |
| DARK PERIOD | ||||||
| Total sleep | SES | 323.8±26.9 | 298.7±20.5 | 328.6±18.0 | 339.6±26.0 | 299.6±25.4 |
| SIS | 299.8±21.2 | 326.2±15.9 | 323±9.5 | 344.9±21.2 | 328.3±16.6 | |
| NREM total | SES | 296±23.7 | 274.7±18.7 | 292.2±17.0 | 313.2±23.8 | 268.7±22.4 |
| SIS | 271.2±19.0 | 295±14.8 | 298.5±10.5 | 320.7±17.4 | 298.9±15.1 | |
| NREM episodes | SES | 139.1±9.9 | 166.8±15.4 | 179.5±24.4* | 179.3±12.8* | 164.9±18.2 |
| SIS | 161.3±15.4 | 162.3±17.3 | 230.3±12.2 | 245.8±19.4 | 188.3±15.0 | |
| NREM duration | SES | 1.97±0.31 | 1.23±0.06 | 1.36±0.16 | 1.36±0.23 | 1.02±0.18 |
| SIS | 1.75±0.22 | 1.33±0.11 | 1.12±0.13 | 1.23±0.12 | 1.14±0.22 | |
| Active wake | SES | 197.8±13.1 | 209.1±25.9 | 203.2±28.1 | 168.8±20.1 | 233.2±32.7 |
| SIS | 212.3±29.4 | 195.7±16.9 | 182.3±11.2 | 156.7±13.8 | 189.1±18.9 | |
| Quiet wake | SES | 198.4±17.3 | 212.2±14.1 | 188.2±13.7 | 211.6±19.2 | 187.2±17.9 |
| SIS | 207.9±16.7 | 198.1±11.0 | 214.6±7.8 | 218.4±13.1 | 202.7±11.5 | |
Comparisons between SES (n = 9) and SIS (n = 9):
*
p < 0.05.
Comparisons to Base: +p < 0.05.
Comparisons to HC:
#
p < 0.05.
Comparisons to AST:
∧
p < 0.01.
Values are means ± SEM. Total Sleep, NREM Total, NREM Duration, Active Wake, and Quiet Wake are reported in minutes. NREM Episodes are reported as number of episodes.