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IgG anti-PA responses at the indicated times following immunization with rPA (CH1603 and CH1609) or γ-d-PGA–rPA conjugate (CHAOA007). Sera collected from chimpanzees at indicated weeks postimmunization were analyzed by ELISA against rPA. Arrows (blue for rPA and green for γ-d-PGA–rPA conjugate) indicate weeks when immunizations were given. The antibody dilutions were log3 transformed and plotted.
