TABLE 2.
Heterosubtypic cellular immune responses pre- and postvaccination in 2010 FLU-v study
| Value by vaccination time | Fold increase in A/Swine/Iowa/15/30 IFN-γ response compared to negative control for groupa: |
|||
|---|---|---|---|---|
| Placebo (n = 7) |
FLU-v (n = 8) |
|||
| Prevaccination | Postvaccination | Prevaccination | Postvaccination | |
| Median | 7.0 | 10.3 | 3.4 | 5.2 |
| Minimum | 1.3 | 3.2 | 1.3 | 1.1 |
| Maximum | 13.0 | 12.1 | 31.8 | 33.5 |
a
Values are represented as the fold increase in IFN-γ response to A/Swine/Iowa/15/30 (H1N1) compared to the negative control. The mean ± SD IFN-γ (pg/ml) responses to the negative control pre- and postvaccination for both groups are 99.2 ± 25.7 versus 80.6 ± 12.9 pg/ml, respectively. The IFN-γ (pg/ml) response to the positive control (ConA) pre- and postvaccination for both groups are 311 ± 85 versus 378 ± 35 pg/ml, respectively.