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. 2015 Jul 30;5:12259. doi: 10.1038/srep12259

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A- Administration of rGal-1 reduces the severity of EAO. EAO score of mice immunized with TH and adjuvants and injected with saline solution (vehicle) or rGal-1. Score evaluated seminiferous tubules, straight tubules, epididymis and vas deferens and includes germ cell loss, inflammation and sperm depletion. Animals with a score below or equal to 5 (…) were considered free of orchitis. B- Inflammation represents the degree of cellular infiltrates in the testicular interstitium and surrounding straight tubules. %: percentage of inflammation. Animals with an inflammation value equal to 0 were considered to be devoid of inflammation. C- Aspermatogenesis represents the percentage of seminiferous tubules with reduction or absence of germ cells. Horizontal lines represent media value. Each symbol represents a single mouse. (^ap < 0.05 vs vehicle).