Table 3.
Bivariate associations of baseline clinical variables and visual parameters at 4 years.
| Baseline Characteristics N = 88 Eyes | VA at 4 Years (logMAR) | VA Change at 4 Years (logMAR) | ≥3 Line Gain at 4 Years | ≥1 Line Loss at 4 Years | ||||
|---|---|---|---|---|---|---|---|---|
| Adjusted Mean (SE) | p Value | Adjusted Mean (SE) | p Value | Number (%) | p Value | Number (%) | p Value | |
| Baseline VA | - | <0.001 | - | 0.002 | - | 0.001 | - | 0.384 |
| 6 month VA | - | <0.001 | - | 0.092 | - | 0.661 | - | 0.169 |
| Total | 0.574 (0.051) | −0.090 (0.044) | 26 (30%) | 20 (23%) | ||||
| Anatomic classification | 0.006 | 0.652 | 0.498 | 0.314 | ||||
| 1 | 0.354 (0.054) | −0.140 (0.054) | 11 (42%) | 5 (25%) | ||||
| 2 | 0.773 (0.185) | −0.105 (0.138) | 3 (12%) | 2 (10%) | ||||
| 3 | 0.599 (0.074) | −0.006 (0.073) | 7 (27%) | 9 (45%) | ||||
| 4 | 0.826 (0.148) | −0.114 (0.137) | 5 (19%) | 4 (20%) | ||||
| Fluorescein classification | 0.573 (0.051) | 0.135 | −0.090 (0.044) | 0.839 | 0.002 | 0.831 | ||
| 1 | 0.442 (0.061) | −0.094 (0.048) | 10 (39%) | 9 (45%) | ||||
| 2 | 0.713 (0.176) | −0.194 (0.166) | 6 (23%) | 3 (15%) | ||||
| 3 | 0.680 (0.089) | −0.022 (0.096) | 9 (35%) | 7 (35%) | ||||
| 4 | 0.650 (0.178) | −0.085 (0.107) | 1 (4%) | 1 (5%) | ||||
| Lesion location | 0.616 | 0.25 | 0.073 | 0.511 | ||||
| foveal | 0.581 (0.061) | −0.136 (0.056) | 23 (89%) | 13 (65%) | ||||
| juxta | 0.636 (0.133) | 0.022 (0.072) | 1 (4%) | 4 (20%) | ||||
| extra | 0.449 (0.139) | 0.036 (0.081) | 2 (8%) | 3 (15%) | ||||
| Lesion area | - | 0.592 | - | 0.043 | - | 0.049 | - | 0.085 |
| Number of injections | - | 0.007 | - | 0.175 | - | 0.57 | - | 0.242 |
VA: visual acuity; logMAR: logarithm of the minimum angle of resolution; SE: standard error.