Table 4.
Multivariate analysis of visual acuity and visual acuity change using baseline clinical parameters over time.
| Time Point | Visual Parameter | Anatomic Classification | Number of Injections | CNV Localization | Overall Lesion Area | Age at First Injection | |
|---|---|---|---|---|---|---|---|
| 6 months | VA | B | 0.06 | −0.05 | −0.04 | 0.01 | 0.01 |
| SE | 0.03 | 0.02 | 0.04 | 0.01 | 0.00 | ||
| p | 0.02 | 0.00 | 0.26 | 0.09 | 0.05 | ||
| VA Change | B | −0.01 | −0.03 | 0.05 | −0.01 | 0.00 | |
| SE | 0.02 | 0.01 | 0.03 | 0.00 | 0.00 | ||
| p | 0.55 | 0.05 | 0.12 | 0.15 | 0.55 | ||
| 12 months | VA | B | 0.07 | −0.06 | −0.03 | 0.01 | 0.01 |
| SE | 0.03 | 0.02 | 0.04 | 0.01 | 0.00 | ||
| p | 0.01 | 0.00 | 0.50 | 0.02 | 0.06 | ||
| VA Change | B | −0.01 | −0.03 | 0.06 | 0.00 | 0.00 | |
| SE | 0.02 | 0.02 | 0.03 | 0.00 | 0.00 | ||
| p | 0.79 | 0.03 | 0.04 | 0.67 | 0.58 | ||
| 24 months | VA | B | 0.06 | −0.07 | −0.02 | 0.02 | 0.01 |
| SE | 0.03 | 0.02 | 0.05 | 0.01 | 0.00 | ||
| p | 0.04 | 0.00 | 0.71 | 0.00 | 0.07 | ||
| VA Change | B | −0.01 | −0.03 | 0.08 | 0.01 | 0.00 | |
| SE | 0.02 | 0.02 | 0.04 | 0.01 | 0.00 | ||
| p | 0.82 | 0.06 | 0.05 | 0.34 | 0.26 | ||
| 36 months | VA | B | 0.09 | −0.09 | 0.02 | 0.01 | - |
| SE | 0.03 | 0.02 | 0.05 | 0.01 | - | ||
| p | 0.00 | <0.001 | 0.65 | 0.05 | - | ||
| VA Change | B | 0.02 | −0.03 | 0.13 | 0.00 | - | |
| SE | 0.03 | 0.02 | 0.05 | 0.01 | - | ||
| p | 0.47 | 0.11 | 0.01 | 0.90 | - | ||
| 48 months | VA | B | 0.11 | −0.11 | 0.01 | 0.00 | - |
| SE | 0.04 | 0.03 | 0.07 | 0.01 | - | ||
| p | 0.01 | 0.00 | 0.87 | 0.89 | - | ||
| VA Change | B | 0.02 | −0.05 | 0.10 | −0.01 | - | |
| SE | 0.04 | 0.03 | 0.07 | 0.01 | - | ||
| p | 0.66 | 0.09 | 0.15 | 0.13 | - |
CNV: choroidal neovascularization; VA: visual acuity; B: beta coefficient; SE: standard error; p: p-value.