Table 2.
Predictive models for the future development of microalbuminuria.
| Feature | Log-Odds ǂ | |
|---|---|---|
| Concentration—Only Model | Concentration—Binding Model | |
| Intercept | 2.725 | 3.313 |
| hsa-miR-105-3p | −0.125 | −0.196 |
| hsa-miR-122-3p | 0.022 | |
| hsa-miR-124-3p | 0.003 | |
| hsa-miR-126-3p | 0.045 | |
| hsa-miR-1972 | −0.003 | −0.054 |
| hsa-miR-28-5p | −0.316 | −0.682 |
| hsa-miR-30b-5p | −0.008 | |
| hsa-miR-363-3p | −0.141 | −0.009 |
| hsa-miR-424-5p | −0.069 | |
| hsa-miR-486-5p | 0.083 | 0.212 |
| hsa-miR-495 | −0.045 | −0.028 |
| hsa-miR-548o-3p | −0.055 | |
| hsa-miR-122-5p X Women | 0.007 | |
| hsa-miR-192-5p X Women | 0.033 | 0.03 |
| hsa-miR-200c-3p X Women | 0.07 | |
| hsa-miR-548o-3p X Women | −0.296 | −0.498 |
| hsa-miR-720 X Women | 0.059 | 0.018 |
ǂ Log-Odds ratios are coefficients that multiply the features (40-Cq) for each of the microRNAs measured in the urine. These terms are then added together to give an overall log-odds score which when exponentiated yields the odds of microalbuminuria development for a given sample. These microRNA measurements carry a different prognostic implication for women. For these microRNAs the log-odds multiply the corresponding feature only for women.