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. Author manuscript; available in PMC: 2015 Jul 30.
Published in final edited form as: Haemophilia. 2013 Nov 22;20(2):230–237. doi: 10.1111/hae.12302

Table 2.

Inhibitor titer elevations detected at enrollment and during the study according to selected demographic and clinical characteristics.

Detected at Enrollment Detected During Study Follow-up Total Detected
Non-Severe 3/9 (33%) 5/14 (36%) 8/23 (35%)
Age >5 years 4/9 (44%) 6/14 (43%) 10/23 (43%)
Exposure Days >150 3/9 (33%) 2/14 (14%) 5/23 (22%)
Exposure Days>20 8/9 (89%) 5/14 (36%) 13/23 (57%)
White Non-Hispanic Ethnicity 7/9 (78%) 10/14 (71%) 17/23 (74%)
High Risk Mutation 8/9 (89%) 10/14 (71%) 18/23 (78%)
Initial Titer >1.0 NBU 4/9 (44%) 11/14 (79%) 15/23 (65%)
Peak Titer >1.0 NBU 4/9 (44%) 11/14 (79%) 15/23 (65%)
Peak Titer >5.0 NBU 2/9 (22%) 5/14 (36%) 7/23 (30%)
No Clinical Indication 9/9 (100%) 5/14 (36%) 14/23 (61%)

NBU = Nijmegen Bethesda Units