Figure 1.
The levels of BubR1 in OSCC cell lines and normal cells. (A) Total RNA was collected after the cells incubation for 24 h. Quantificative analysis of BubR1 mRNA in various OSCC cell lines, and in both normal human oral keratinocytes (HOK) and human gingival fibroblasts (HGF), was examined by a quantitative reverse transcription PCR. Error bars show standard deviation of three independent experiments in duplicate. a vs. a, >0.05; a vs. b, <0.05; a vs. c, <0.001; (B) The protein expression of BubR1, MMP-9, and MMP-2 in a panel of OSCC cell lines compared to normal human oral keratinocytes (HOK) and human gingival fibroblasts (HGF).