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Effects of baicalin on aristolochic acid I (AAI) nephrotoxicity. Blood samples were collected to obtain serum for the measurement of blood urea nitrogen (BUN) (A) and creatinine (CRE) (B); (C) Kidneys were collected to perform hematoxylin and eosin (H&E) staining. Arrowheads, tubular dilation; stars, tubular necrosis and granular casts. Scale bar, 100 μm. Data are expressed as the mean ± SD (n = 5). *** p < 0.001 versus the control, ## p < 0.01 versus the AAI only group.
