Skip to main content
. 2015 Jul 20;16(7):16454–16468. doi: 10.3390/ijms160716454

Figure 5.

Figure 5

Baicalin increased the expression of CYP1A1 and CYP1A2 at the mRNA and protein level in mouse livers. Mice were treated with baicalin (80 mg/kg) for three days in the presence or absence of resveratrol (RES) (50 mg/kg), another specific antagonist of AhR. mRNA epressions of CYP1A2 (A) and CYP1A1 (C) were determined with real-time PCR and data were normalized to that of GAPDH; Liver microsomes were extracted and separated by SDS-PAGE. Protein expressions of CYP1A2 (B) and CYP1A1 (D) were assessed by Western blot and data were normalized to that of cytochrome P450 reductase (CPR). Data are expressed as the mean ± SD (n = 5). ** p < 0.01, *** p < 0.001 versus the control group; # p < 0.05, ## p < 0.01, versus the baicalin only group.