TABLE 2.
Characteristics of sentinel lymph node biopsy patients
| SLNB performed (N = 62) | Positive SLNB (N = 18) | Negative SLNB (N= 44) | p value | |
|---|---|---|---|---|
| Age group | ||||
| <12 years | 2 | 1 | 1 | |
| 12–17 years | 32 | 9 | 23 | |
| 18–20 years | 28 | 8 | 20 | |
| Gender, n (%) | NS | |||
| Male | 28 (45.2) | 9 (50) | 19 (43.2) | |
| Female | 34 (54.8) | 9 (50) | 25 (56.8) | |
| Histologic type, n (%) | NS | |||
| Superficial spreading | 29 (46.8) | 6 (33.3) | 23 (52.3) | |
| Nodular | 14 (22.6) | 5 (27.8) | 9 (20.5) | |
| Spitzoid | 3 (4.8) | 1 (5.6) | 2 (4.5) | |
| Other | 4 (6.5) | 1 (5.6) | 3 (6.8) | |
| Not specified | 12 (19.4) | 5 (27.8) | 7 (15.9) | |
| Location, n (%) | NS | |||
| Head and neck | 24 (38.7) | 5 (27.8) | 19 (43.2) | |
| Trunk | 18 (29) | 6 (33.3) | 12 (27.3) | |
| Extremities | 20 (32.2) | 7 (38.9) | 13 (29.5) | |
| Breslow thickness (mm) | ||||
| Median | 1.60 | 2.55 | 1.30 | <0.05* |
| Range | 0.42–10.4 | 1.05–6.2 | 0.42–10.4 | |
| Mitotic rate, n (%)a | NS | |||
| ≥1/mm2 | 25 (67.6) | 12 (85.7) | 13 (56.5) | |
| <1/mm2 | 12 (32.4) | 2 (14.3) | 10 (43.5) | |
| Ulceration, n (%)a | 17 (35.4) | 8 (57.1) | 9 (26.5) | NS |
| Regression, n (%)a | 2 (5.0) | 1 (9.1) | 1 (3.4) | NS |
| VGP, n (%)a | 37 (94.9) | 11 (100) | 26 (92.9) | NS |
| LVI, n (%)a | 1 (2.6) | 1 (8.3) | 0 | NS |
SLNB sentinel lymph node biopsy, VGP vertical growth phase, LVI lymphovascular invasion, NS not significant
*
Significant on univariate analysis for Breslow thickness versus SLNB status
a
Data unavailable or missing for mitotic rate in 25 cases, for ulceration in 14 cases, for regression in 22 cases, for VGP in 23 cases, and for LVI in 23 cases