Table 5.
Hypergeometric enrichment analysis of 21 genes in peripheral blood cells from healthy samples
| Related Cell | Common Targets with ≥3-Fold of Median Intensity | Mapped Upregulated Probes in TOL (n) | Hypergeometric P Value |
|---|---|---|---|
| Dendritic cells | 3922 | 7 | 0.01 |
| B cells | 5028 | 7 | 0.05 |
| CD56+ NK cells | 3802 | 6 | 0.04 |
| CD8+ T cells | 3278 | 3 | 0.26 |
| CD4+ T cells | 3157 | 3 | 0.25 |
| Monocytes | 3241 | 3 | 0.26 |
| CD34+ cells | 3898 | 3 | 0.27 |
| CD33+ cells | 11,218 | 4 | 0.21 |
Frequency and hypergeometric P values for common targets between BioGPS from HU133A platform (GSE1133) and identified 18 upregulated targets specific to tolerance from Agilent platform and P values of enrichment across related blood cell types are shown.