Table 2.
AUCs for prediction of progression to AKI stage 3
| Biomarker | AUC±SEM | P Value for Biomarker Alone | P Value Compared With FST alone | AUC of Biomarker and FST±SEM | P Value for Biomarker and FST Compared With FST Alone |
|---|---|---|---|---|---|
| FST (2-hr UOP) | 0.87±0.05 | <0.001 | NA | NA | NA |
| Urine NGAL | 0.65±0.06 | 0.04 | 0.002 | 0.84±0.05 | 0.10 |
| Urine IL-18 | 0.65±0.07 | 0.04 | 0.009 | 0.85±0.05 | 0.89 |
| Urine KIM-1 | 0.63±0.06 | 0.07 | 0.007 | 0.86±0.05 | 0.79 |
| Uromodulin | 0.54±0.07 | 0.54 | 0.002 | 0.85±0.05 | 0.94 |
| Urine IGFBP-7 | 0.62±0.09 | 0.20 | <0.001 | 0.88±0.05 | 0.57 |
| Urine TIMP-2 | 0.70±0.08 | 0.03 | 0.02 | 0.83±0.06 | 0.20 |
| Urine IGFBP-7×TIMP-2 | 0.69±0.08 | 0.04 | 0.01 | 0.90±0.06 | 0.35 |
| Urine Creatinine | 0.48±0.08 | 0.77 | <0.001 | 0.84±0.06 | 0.85 |
| Urine ACR | 0.56±0.07 | 0.45 | 0.002 | 0.84±0.06 | 0.32 |
| FeNa | 0.51±0.07 | 0.92 | <0.001 | 0.83±0.06 | 0.47 |
| Plasma NGAL | 0.75±0.08 | 0.007 | 0.10 | 0.86±0.07 | 0.53 |
NA, not applicable; ACR, albumin-to-creatinine ratio.