Table 5.
Prediction of the composite of AKIN stage 3 and death
| Biomarker | AUC±SEM | P Value for Biomarker Alone | P Value Compared With FST alone | AUC of Biomarker and FST±SEM | P Value for Biomarker and FST Compared With FST Alone |
|---|---|---|---|---|---|
| FST (2-hr UOP) | 0.81±0.06 | <0.0001 | NA | NA | NA |
| Urine NGAL | 0.69±0.06 | 0.006 | 0.07 | 0.82±0.06 | 0.89 |
| Urine IL-18 | 0.63±0.07 | 0.07 | 0.009 | 0.82±0.06 | 0.87 |
| Urine KIM-1 | 0.64±0.06 | 0.04 | 0.04 | 0.82±0.06 | 0.81 |
| Uromodulin | 0.54±0.07 | 0.58 | 0.004 | 0.85±0.06 | 0.31 |
| Urine IGFBP-7 | 0.65±0.08 | 0.07 | 0.19 | 0.79±0.08 | 0.80 |
| Urine TIMP-2 | 0.66±0.08 | 0.06 | 0.18 | 0.80±0.08 | 0.75 |
| Urine IGFBP-7×TIMP-2 | 0.68±0.08 | 0.03 | 0.27 | 0.78±0.08 | 0.93 |
| Urine Creatinine | 0.54±0.07 | 0.56 | 0.007 | 0.83±0.06 | 0.23 |
| Urine ACR | 0.50±0.07 | 0.96 | 0.002 | 0.82±0.06 | 0.32 |
| FeNa | 0.49±0.07 | 0.84 | 0.009 | 0.80±0.06 | 0.31 |
| Plasma NGAL | 0.69±0.08 | 0.03 | 0.27 | 0.80±0.08 | 0.76 |
NA, not applicable; ACR, albumin-to-creatinine ratio.