Table 2.
From | To | Mean | SE | Source | Probabilistic Sensitivity Analysis | ||
---|---|---|---|---|---|---|---|
Distribution | Lower | Upper | |||||
F0-F2 | F3 | 0.025 | 0.004 | [21, 32] | Beta | 0.018 | 0.033 |
F3 | F4 | 0.037 | 0.007 | [21, 32] | Beta | 0.025 | 0.052 |
F4 | DCC | 0.039 | 0.010 | [21, 33] | Beta | 0.022 | 0.061 |
HCC | 0.014 | 0.010 | [21, 33] | Beta | 0.002 | 0.039 | |
SVR F4 | DCC | 0.000 | 0.000 | expert opinion | Beta | 0.000 | 0.000 |
HCC | 0.005 | 0.001 | [34] | Beta | 0.004 | 0.007 | |
DCC | HCC | 0.014 | 0.010 | [21, 33] | Beta | 0.002 | 0.039 |
LT | 0.020 | 0.003 | [21, 35] | Beta | 0.015 | 0.026 | |
LrD | 0.130 | 0.010 | [21, 33] | Beta | 0.111 | 0.150 | |
HCC | LT | 0.020 | 0.003 | [32, 35] | Beta | 0.015 | 0.026 |
LrD | 0.430 | 0.030 | [21, 33] | Beta | 0.372 | 0.489 | |
LT | LrD | 0.150 | 0.023 | [21, 36] | Beta | 0.109 | 0.197 |
pLT | LrD | 0.057 | 0.009 | [21, 36] | Beta | 0.041 | 0.075 |
All-cause mortality | Age/gender specific | Life Tables, German Federal Office of Statistics |
DCC decompensated cirrhosis, HCC hepatocellular carcinoma, SVR sustained virologic response, LT liver transplant, LrD Liver related death, pLT post liver transplant, fibrosis states F0-F4 according to METAVIR