Table 3.
Genotype frequencies of XAB2 and their association with non-small cell lung cancers
| XAB2 Genotypes | Controls (n = 470) | Cases (n = 470) | OR (95 % CI)a | P valuea | ||
|---|---|---|---|---|---|---|
| No | (%) | No | (%) | |||
| rs4134816 | ||||||
| TT | 429 | 91.3 | 450 | 95.7 | ||
| CT | 40 | 8.5 | 20 | 4.3 | 0.49 (0.28–0.86) | 0.012 |
| CC | 1 | 0.2 | 0 | 0.0 | NC | |
| CT + CC | 41 | 8.7 | 20 | 4.3 | 0.46 (0.26–0.84) | 0.010 |
| rs4134819 | ||||||
| AA | 122 | 26.0 | 126 | 26.8 | ||
| AG | 226 | 48.0 | 237 | 50.4 | 0.96 (0.70–1.31) | 0.797 |
| GG | 122 | 26.0 | 107 | 22.8 | 0.81 (0.56–1.16) | 0.251 |
| rs794083 | ||||||
| CC | 221 | 47.0 | 249 | 53.0 | ||
| CG | 189 | 40.2 | 161 | 34.2 | 0.72 (0.54–0.96) | 0.023 |
| GG | 60 | 12.8 | 60 | 12.8 | 0.87 (0.58–1.31) | 0.517 |
| rs4134860 | ||||||
| TT | 341 | 72.6 | 332 | 70.7 | ||
| CT | 118 | 25.1 | 120 | 25.5 | 1.01 (0.75–1.36) | 0.962 |
| CC | 11 | 2.3 | 18 | 3.8 | 1.73 (0.80–3.75) | 0.163 |
| rs794078 | ||||||
| GG | 365 | 77.7 | 374 | 79.6 | ||
| AG | 93 | 19.8 | 94 | 20.0 | 0.97 (0.70–1.35) | 0.871 |
| AA | 12 | 2.5 | 2 | 0.4 | 0.12 (0.03–0.54) | 0.006 |
| AG + AA | 105 | 22.3 | 96 | 20.4 | 0.87 (0.64–1.20) | 0.396 |
aData were calculated by logistic regression and adjusted for sex, age (categories), and smoking status