Table 1.

Glycosylation using glycosyl donors with various ester-protecting groups at C2

	Acceptors
1a P=Ac X= O-trichloroacetimidateb	84% (α:β 1:1)	NA
1b P=Bz X= O-trichloroacetimidateb	NA	86% (α only)
1c P = ClCH2CO X = O-trichloroacetimidateb	NA	85% (α only)
1d P=CH3OCO X = O-trichloroacetimidateb	85% (α:β 1:1)	83% (α only)
1e P = (CH3)3CCO X = O-trichloroacetimidateb	80% (α only)	81% (α:β 2:3)
1f P = (CH3)3CCO X = SPhc	NA	82% (α:β 1:3)

^aCompound 1a–e, R₁ = Ac, R₂ = Ac; compound 1f, R₁:R₂ = CHPh.

^bActivation with TMSOTf.

^cActivation with NIS/AgOTf.