Recurrent grade III or IV glioma
KPS ≥ 60, life expectance > 8 weeks.
≥4 vaccines available for use
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Treatment with corticosteroids at time of resection
Hx of immunodeficiency, immunosuppressive drug use excluding corticosteroids, current malignancies at other sites or other cancers within 5 years
Uncontrolled active infection
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