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. 2015 Jul 30;11(7):e1005415. doi: 10.1371/journal.pgen.1005415

Fig 4. Inhibition of BMP signaling is crucial for initiation of reprogramming.

Fig 4

(A) IF /IHC staining of pSMAD 1 /5 in parental and xenografted TCam-2 at indicated time points. Scale bar: 100 μm. (B, C) qRT-PCR analysis of indicated genes after NOGGIN treatment of TCam-2 cells for 1–8 days. (D) Western blotting of indicated proteins 8 days after NOGGIN treatment of TCam-2 cells.