Table 2. Laboratory findings and cardiac function measurements on the first study day in subjects with dengue.
| Diagnosis | |||
|---|---|---|---|
| DF | DHF (no leakage) a | DHF(leakage) | |
| Number | 119 | 24 | 36 |
| Fever day | .34 | .83 (.007) | 0 (.013) b |
| Liver enzymes | |||
| AST, IU/ml | 126 (11) | 142(22) | 636(408) |
| ALT, IU/ml | 61 (6) | 65(14) | 202(102) |
| Platelet counts, cells/μl | 115932 (3807) | 86125. (7362) | 41638(3014) b |
| Hematocrit, % | 38 (.4) | 40.0(.78) | 41.7 (.84) |
| Albumin, g/dl | 3.99 (.42) | 3.8 (.05) | 3.3 (.09) b |
| Cardiac enzymes | |||
| Troponin-T (pg/ml) | 4.72 (2.9) | 5.98 (2.1) | 4.9 (.6) |
| CPK-MB (ng/ml) | 11.4 (.6) | 10.3 (.5) | 11.4 (1.3) |
| HR, beats/min | 91 (1.4) | 94 (3.7) | 99 (2.6) |
| Pulse pressure, mm Hg | 32.7 (0.6) | 32.2(1.8) | 22.5(1.3) b |
| Stroke volume (ml) | 41.4 (1.3) | 43.6 (3.1) | 30.0 (2.6) b |
| Cardiac index (L/min/m2). | 3189 (75) | 3173 (857) | 2695 (767) c |
| SVR (dynes-s/cm5) | 1795 (63) | 1820 (133) | 2478 (184) b |
| Left ventricular systolic functions | |||
| EF, % | 68.1 (1.3) | 67.6 (1.3) | 64.3 (1.2)(p = .068 compared to DHF (no leakage) |
| Left ventricular diastolic functions | |||
| MV-E (cm/s) | 99.9 (6.63) | 94.6 (3.8) | 75.4 (2.5) b |
| MV-A (cm/s) | 56.50(1.34) | 54.63 (2.78) | 49.73 (1.79) |
| MV-E/A | 2.02(.125) | 1.79 (0.8) | 1.56 (0/6) c |
| Intravascular volume indicator | |||
| Inferior vena cava diameter, mm | 10.22 (.34) | 11.25 (.76) | 8.42 (.62) c |
Values represent mean (SE), or number of cases.
a two DHF cases did not have ultrasonography performed on the day of enrollment and were not included in this analysis. Differences between groups were analyzed by ANOVA with post hoc test or by Man Whitney’s test.
b, c different from DHF without leakage at P < .005, and .05 respectively).