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. 2015 Jul 30;10(7):e0134499. doi: 10.1371/journal.pone.0134499

Fig 5. MAPK activation changes after enrichment of IGL-1 solution with CA II.

Fig 5

Western blotting and densitometric analysis of p-38 (A); p-ERK (B) and p-JNK (C) in steatotic liver after 120 min of normothermic “ex vivo” perfusion. CA II addition to IGL-1 solution prevented MAPK activation. Ctr 2: Liver flushed and perfused “ex-vivo” without cold preservation; IGL-1: liver preserved in IGL-1 solution (4°C, 24 h) and subjected to 2h-normothermic “ex vivo” perfusion. IGL-1+CAII: liver preserved in IGL-1 solution (4°C, 24 h) enriched with CA II and subjected to 2h- normothermic “ex vivo” perfusion. * p < 0.05 vs Ctr 2; # p < 0.05 vs IGL-1.