Table 1.
Pattern recognition receptors | |||||||
---|---|---|---|---|---|---|---|
TLR3 | TLR7 | TLR11–12 | RIG-I | MDA5 | NOD1 | NLRC4 | |
Batf3-dependent DC | + | − | + | − | − | − | − |
Batf3-independent DC | − | −/+ | −/+ | + | + | −/+ | −/+ |
References | Edwards 2003 | Edwards 2003 | Yarovinsky 2005 | Luber 2010 | Luber 2010 | Luber 2010 | Luber 2010 |
Lectin-like receptors | ||||||||
---|---|---|---|---|---|---|---|---|
CD205 | CD207 | CD209 | 33D1 | Clec7a | Clec9a | Clec12a | CD24 | |
Batf3-dependent DC | ++ | int/− | − | − | − | + | ++ | ++ |
Batf3-independent DC | + | − | + | −/+ | + | − | + | + |
References | Shortman 2010 | Shortman 2010 | Our data | Dudziak 2007 | Shortman 2010 | Shortman 2010 | Shortman 2010 | Shortman 2010 |
Other differential cell markers | |||||||
---|---|---|---|---|---|---|---|
CD36 | Sirpa | CX3CR1 | F4/80 | XCR1 | Cystatin C | Necl2 | |
Batf3-dependent DC | + | − | − | − | + | + | − |
Batf3-independent DC | − | + | −/+ | + | − | − | + |
References | Shortman 2010 | Lahoud 2006 | Ginhoux 2009 | Ginhoux 2009 | Domer 2009 | Shortman 2010 | Galibert 2005 |
This table summarizes published data on differential expression of Toll-like receptors (Edwards et al., 2003; Luber et al., 2010; Yarovinsky et al., 2005), lectin-like receptors (Dudziak et al., 2007; Shortman and Heath, 2010), and other cell markers (Dorner et al., 2009; Galibert et al., 2005; Ginhoux et al., 2009; Lahoud et al., 2006; Shortman and Heath, 2010) between Batf3-IRF8-Id2 dependent DCs (including CD8+and/or CD103+DCs) and Batf3-IRF8-Id2- independent DCs.