Table I.

Proteostasis signature genes regulated by HSF1 in T cells

Gene Title	Gene Symbol	Log2 (KO37/WT37)	P-Value	Log2 (KO40/WT40)	P-Value
AHA1, activator of heat shock 90kDa protein ATPase homolog 1	Ahsa1	−0.74	0.002	−0.85	0.001
Autophagy-related 7 (yeast) (Atg7)	Apg7l	0.50	0.009	0.55	0.008
Beta-2 microglobulin (B2m), mRNA	B2m	0.69	0.002	0.90	0.001
Bcl2-associated athanogene 3	Bag3	−1.01	0.005	−1.41	0.002
Cullin 1	Cul1	1.40	0.001	0.34	0.125
DnaJ (Hsp40) homolog, subfamily A, member 1	Dnaja1	−0.99	0.008	−1.08	0.006
DnaJ (Hsp40) homolog, subfamily A, member 4	Dnaja4	−1.26	0.005	−0.90	0.013
DnaJ (Hsp40) homolog, subfamily B, member 1	Dnajb1	−0.91	0.000	−1.04	0.000
FK506 binding protein 4	Fkbp4	−0.61	0.008	−0.74	0.003
Histone deacetylase 5	Hdac5	0.76	0.001	0.25	0.153
Hect domain and RLD 4 (Herc4), mRNA	Herc4	0.64	0.007	0.19	0.180
Heat shock factor 1	Hsf1	−0.70	0.011	−0.99	0.003
Heat shock factor 2	Hsf2	0.58	0.014	1.22	0.001
Heat shock protein 110	Hsp110	−1.80	0.001	−1.64	0.001
Heat shock protein 1A	Hspa1a	−3.55	0.003	−4.51	0.001
Heat shock protein 1B	Hspa1b	−4.00	0.001	−4.79	0.000
Heat shock protein 8	Hspa8	−0.54	0.025	−0.68	0.009
Heat shock protein 1, alpha	Hspca	−0.51	0.011	−0.61	0.005
Heat shock protein 1, beta	Hspcb	−0.38	0.001	−0.50	0.000
Heat shock protein 1 (chaperonin 10)	Hspe1	−0.77	0.009	−0.94	0.004
Lectin, mannose-binding 2-like	Lman2l	−0.89	0.005	−0.88	0.002
Stress-induced phosphoprotein 1	Stip1	−0.75	0.005	−0.79	0.003