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The subgroups evaluated were: culture-negative IE (CN-IE), non-staphylococcal IE (non-S IE), and staphylococcal IE (S IE). Elevated proportion of high producers of IL-1β, TNF-α and IL-12 was observed only in the S IE subgroup. The prevalence of high producers of IL-10 was lower in the S IE subgroup as compared to the others subgroups.
