Table 3. Overall (OS) and disease-free (DFS) survival in relation to SNP distributions (Cox regression).
| Genotype | OS | DFS | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Cases | Events | HR | 95% CI | P | Events | HR | 95%CI | P | |
| rs17878362 | |||||||||
| A 1 A 1 | 470 | 52 | REF | - | - | 78 | REF | - | - |
| A 1 A 2 | 163 | 16 | 0.87 | 0.50–1.52 | 0.63 | 24 | 0.88 | 0.56–1.39 | 0.58 |
| A 2 A 2 | 24 | 3 | 1.07 | 0.33–3.43 | 0.91 | 8 | 2.15 | 1.04–4.44 | 0.04 |
| A 1 A 2 + A 2 A 2 | 187 | 19 | 0.90 | 0.53–1.52 | 0.69 | 32 | 1.03 | 0.68–1.56 | 0.88 |
| rs1042522 | |||||||||
| GG | 369 | 44 | REF | - | - | 71 | REF | - | - |
| GC | 271 | 25 | 0.82 | 0.50–1.34 | 0.42 | 33 | 0.66 | 0.44–1.00 | 0.05 |
| CC | 55 | 4 | 0.62 | 0.22–1.71 | 0.35 | 9 | 0.88 | 0.44–1.75 | 0.71 |
| GC+CC | 326 | 29 | 0.78 | 0.49–1.25 | 0.30 | 42 | 0.70 | 0.48–1.02 | 0.06 |
| rs12947788 | |||||||||
| CC | 592 | 63 | REF | - | - | 97 | REF | - | - |
| CT | 99 | 11 | 1.06 | 0.56–2.00 | 0.87 | 16 | 1.00 | 0.59–1.70 | 0.99 |
| TT | 5 | 0 | - | - | - | 0 | - | - | - |
| CT+TT | 104 | 11 | 1.00 | 0.53–1.90 | 0.99 | 16 | 0.95 | 0.56–1.61 | 0.85 |
The SNP rs17884306 was monomorphic in cases, thus not presented.
HR, hazard ratio; 95% CI, confidence interval. Significant results in bold.